Science & R&D

Species-level resolution, explainable models

Our analyses rely on shotgun metagenomic sequencing rather than 16S: all DNA in the sample is read, microorganisms are identified at species and strain level, and functional genes and metabolic pathways are evaluated together.

Method

The scientific flow from sample to report

01

Sample stabilisation

A buffer that preserves DNA at room temperature; stable for up to 14 days without a cold chain.

02

DNA isolation and sequencing

Isolation with standard kits, shotgun sequencing on the Illumina platform; target depth ≥ 5 million read pairs per sample.

03

Bioinformatics

Quality filtering, host-DNA removal, taxonomic profiling (species/strain) and functional annotation (KEGG, MetaCyc pathways).

04

Scoring and interpretation

Scores normalised against a reference population; gradient boosting models with SHAP explainability; report delivered with dietitian review.

Why shotgun

Compared with 16S

16S rRNAShotgun metagenomics
ResolutionGenus levelSpecies and strain level
Functional informationIndirect inferenceDirect gene and pathway readout
CoverageBacteria and archaeaBacteria, archaea, fungi, viruses
Comparison on repeat testingLimitedTrackable at species and function level
Ongoing projects

R&D portfolio

TÜBİTAK 1507

CRCBIOME

Microbiome- and cfDNA-based assessment of early colorectal cancer risk signals; 2026–2028.

TÜBİTAK 1507

Women in Performance

Tracking recovery, inflammation and performance in women athletes through microbiome signatures; 2026–2028.

International collaboration

Max Delbrück Center, Berlin

A multi-omics study combining microbiome and cfDNA.

Programme

EIT Health Jumpstarter 2026

Selected for Europe's health innovation programme with the CRC vertical.

Limits

What we do not claim

Microbiome analysis alone does not diagnose disease and is not used on its own for treatment decisions. Scores and interpretive panels are not direct measurements of hormones, histamine, inflammation, sleep quality or gut permeability. We pursue our clinical and economic claims as targets for prospective validation and share results within that frame.

Start getting to know your gut today

Write to us about kit orders, partnerships or collaboration; we reply within one business day.